Publications

MalarVx, Inc Publications

  • “Purification and production of Plasmodium falciparum zygotes from in vitro culture using magnetic column and Percoll density gradient”. Malaria Journal 2020 Zhou Y, Grieser AM, Do J, Itsara LS, Vaughan AM, Ghosh AK.   PMID: 32450861   
  • “The Development of Whole Sporozoite Vaccines for Plasmodium falciparum Malaria”. Review Front Immunol 2018 Itsara LS, Zhou Y, Do J, Grieser AM, Vaughan AM, Ghosh AK.   PMID: 30619241     
  • “PfCap380 as a marker for Plasmodium falciparum oocyst development in vivo and in vitro.” Malaria Journal 2018 Itsara LS, Zhou Y, Do J, Dungel S, Fishbaugher ME, Betz WW, Nguyen T, Navarro MJ, Flannery EL, Vaughan AM, Kappe SHI, Ghosh AK.  PMID: 29609625

 

Publications

  • “A replication-competent late liver stage-attenuated human malaria parasite.” JCI Insight 2020 Goswami D, Betz W, Locham NK, Parthiban C, Brager C, Schäfer C, Camargo N, Nguyen T, Kennedy SY, Murphy SC, Vaughan AM, Kappe SH. PMID: 32484795
  • “An Alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates.” Science Translational Medicine 2020 Erasmus JH, Khandhar AP, O'Connor MA, Walls AC, Hemann EA, Murapa P, Archer J, Leventhal S, Fuller JT, Lewis TB, Draves KE, Randall S, Guerriero KA, Duthie MS, Carter D, Reed SG, Hawman DW, Feldmann H, Gale M Jr, Veesler D, Berglund P, Fuller DH.       PMID: 32690628
  • “Innate immunity limits protective adaptive immune responses against pre-erythrocytic malaria parasites.” Nat Commun. 2019 Minkah NK, Wilder BK, Sheikh AA, Martinson T, Wegmair L, Vaughan AM, Kappe SHI.  PMID: 31477704
  • “Malaria Vaccines: Recent Advances and New Horizons.” Cell Host Microbe 2018 Draper SJ, Sack BK, King CR, Nielsen CM, Rayner JC, Higgins MK, Long CA, Seder RA.    PMID: 30001524
  • “Humanized Mouse Models for the Study of Human Malaria Parasite Biology, Pathogenesis, and Immunity.” Front Immunol. 2018 Minkah NK, Schafer C, Kappe SHI.     PMID: 29725334
  • “A Plasmodium berghei sporozoite-based vaccination platform against human malaria.” NPJ Vaccines 2018 Mendes AM, Machado M, Gonçalves-Rosa N, Reuling IJ, Foquet L, Marques C, Salman AM, Yang ASP, Moser KA, Dwivedi A, Hermsen CC, Jiménez-Díaz B, Viera S, Santos JM, Albuquerque I, Bhatia SN, Bial J, Angulo-Barturen I, Silva JC, Leroux-Roels G, Janse CJ, Khan SM, Mota MM, Sauerwein RW, Prudêncio M. PMID: 30155278
  • “Complete attenuation of genetically engineered Plasmodium falciparum sporozoites in human subjects”. Science Translational Medicine 2017 Kublin JG, Mikolajczak S, Sack BK, Fishbaugher M, Seilie A, Shelton L, VonGoedert T, First M, Magee S, Fritzen E, Betz W, Kain H, Dankwa DA, Steel RW, Vaughan AM, Sather N, Murphy SC, Kappe SH. 
  • “Towards functional antibody-based vaccines to prevent pre-erythrocytic malaria infection.” Expert Rev Vaccines 2017 Sack B, Kappe SH, Sather DN.     PMID: 28277097
  • “Novel approaches to whole sporozoite vaccination against malaria.” 2015 Bijker EM, Borrmann S, Kappe SH, Mordmüller B, Sack BK, Khan SM.    PMID: 26469716